Punit Gupta
D.K.S. Post Graduate Institute And Research Center, India
Title: Comparison of infection episodes in CKD patients with or without hemodialysis from tribal population
Biography
Biography: Punit Gupta
Abstract
Chronic kidney diseases (CKD) are a progressive and irreversible deterioration of renal function. Patients with CKD are prone to a variety of infections. Further chronic hemodialysis increases the infections and related morbidity and mortality. The present study was conducted to assess the probability of infection episode in CKD patients in patients with or without hemodialysis. A Cross sectional observational study was conducted with a total 56 patients with CKD. Clinical and biochemical data related to infections were collected from the individual patient records. The results showed that the chills and rigors, increased TLC, and elevated ESR were found to more in CKD patients on chronic hemodialysis. Further, our results suggested that CKD patient population showed increased-risk for the development of lethal sepsis. Hence, identification of the causes of infection and the appropriate treatment based on the severity of symptoms are essential for CKD patients who are on dialysis.
MATERIALS AND METHOD
A Cross sectional observational study was conducted in the nephrology unit, Department of Medicine, Dr. Bhimrao Ambedkar Hospital Raipur (C.G.) For this study a total 56 patients with CKDwere recruited during February to March, 2018. Institutional ethical committee of the Pt.J.N.M. Medical college Raipur has approved the study protocol. All patients provided the written informed consent before participating in the study. An approved pre-structured tools or format was used to collect the information that include basic parameters suchas age, sex, diabetes millitus, hemoglobin, complete blood count, CRP, Urea, Creatinine, sodium, potassium, urine routine, Thyroid, number of dialysis undergone, site of center line for hemodialysis, urine culture, X-RAY Chest and usg abdomen were collected from the individual patient records. In this study increased ESR and TLC (>11000/L) was considered as an indicator for infection. CKD staging of diseases has been calculated by MDRD formula. Data was collected by using indirect method and was entered and analysed by using Microsoft Excel. The data was presented as number and percentage in each group.