Kidney Transplantation, Xenotransplantation & Organ Preservation

Kidney transplantation is advancing with improved immunosuppressive strategies, donor-matching algorithms, and organ-preservation techniques. Hypothermic and normothermic machine perfusion enhances graft viability and reduces delayed graft function. Xenotransplantation research using gene-edited pig organs offers potential solutions to donor shortages. Tolerance-inducing therapies, such as cellular immunomodulation and regulatory T-cell expansion, reduce rejection and long-term complications. Enhanced diagnostics support early detection of rejection biomarkers, ensuring timely intervention and better graft survival.

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