27^th Global Nephrology, Urology and Kidney Failure Congress

Regenerative Kidney Therapies & Cellular Repair Technologies

Regenerative kidney therapies focus on reversing renal damage through stem cell engineering, organoid development, tissue scaffolds, and molecular reprogramming. Advanced technologies harness mesenchymal stem cells, induced pluripotent stem cells, and endothelial progenitors to restore nephron structures, reduce inflammation, and promote vascular regeneration. Bioengineered kidney organoids allow researchers to model disease progression, test drug responses, and design personalized therapies. Gene-editing platforms, including CRISPR, support correction of disease-causing mutations, opening pathways for curative treatments. Novel extracellular vesicle-based therapeutics provide cell-free regenerative signals that enhance tubular repair and reduce fibrosis. Combined with biomaterial scaffolds and 3D bioprinting, these approaches accelerate nephron reconstruction in both acute and chronic disease settings. As regenerative nephrology advances, it strengthens the possibility of delaying dialysis, reducing transplant dependence, and enabling long-term renal restoration.