Tubular and Interstitial Diseases

Tubulointerstitial diseases are clinically diverse conditions that share similar features of tubular and interstitial injury. In severe and sustained cases, the entire kidney may turn out to be involved, with glomerular dysfunction and even renal failure. The prime categories of tubulointerstitial disease are

  1. Acute tubular necrosis
  2. Acute or chronic tubulointerstitial nephritis
  3. Contrast nephropathy is acute tubular necrosis caused by an iodinated radiocontrast agent.
  4. Analgesic nephropathy is a type of chronic interstitial nephritis, and reflux nephropathy and myeloma kidney can involve chronic tubulointerstitial nephritis.
  5. Tubulointerstitial disorders can also result from metabolic disturbances and exposure to toxins.

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