26^th Global Nephrology, Urology and Kidney Failure Congress

Genetics of Kidney Disease

Understanding the genetics of kidney disease has opened new avenues for diagnosis, treatment, and prevention. Genetic factors play a crucial role in the predisposition to various kidney disorders, including polycystic kidney disease (PKD), focal segmental glomerulosclerosis (FSGS), and congenital anomalies of the kidney and urinary tract. Advances in genomic technologies, such as next-generation sequencing, have enabled the identification of specific genetic mutations associated with these conditions, facilitating earlier and more accurate diagnoses. Genetic counselling can provide patients and families with valuable information about inheritance patterns and potential risks for future generations. Additionally, ongoing research into gene therapy and precision medicine holds promise for developing targeted treatments that address the underlying genetic causes of kidney diseases. Understanding the genetic basis of these conditions also aids in the identification of biomarkers for disease progression, allowing for personalized monitoring and management strategies. As the field of nephrology embraces genetic insights, it heralds a new era of tailored interventions aimed at improving outcomes for individuals with kidney disease.