26^th Global Nephrology, Urology and Kidney Failure Congress

Understanding Glomerular Diseases

Glomerular diseases encompass a diverse group of conditions affecting the kidney's filtering units, the glomeruli. These diseases can lead to significant kidney damage and are characterized by symptoms such as proteinuria, haematuria, and renal dysfunction. Understanding the underlying mechanisms of glomerular diseases is crucial for effective diagnosis and treatment. Conditions like minimal change disease, focal segmental glomerulosclerosis (FSGS), and glomerulonephritis can result from various etiologist, including autoimmune disorders, infections, or genetic factors. Diagnosis typically involves a combination of clinical evaluation, laboratory tests, and often renal biopsy to ascertain the specific type and cause of the disease. Treatment options vary widely, ranging from corticosteroids and immunosuppressant’s to more advanced therapies like monoclonal antibodies targeting specific pathways. Emerging research focuses on identifying biomarkers for early detection and monitoring of disease progression, aiming to tailor therapies to individual patients. With advancements in understanding glomerular pathophysiology, there is hope for more effective management strategies and improved outcomes for those affected by these complex kidney disorders.